Table 4

Period effects on cardiovascular risk factors after 3 and 6 months in all 13 subjects combined (mean ± SD)

Baseline

3 months

6 months

P*


HbA1C (%, Mono-S)

6.6 ± 0.6

5.9 ± 0.9

5.6 ± 0.6

0.10

Cholesterol (mmol/l)

4.4 ± 1.1

4.4 ± 1.1

4.3 ± 1.3

0.6

LDL (mmol/l)

2.9 ± 0.9

2.8 ± 1.0

2.7 ± 1.0

0.5

HDL (mmol/l)

1.3 ± 0.2

1.3 ± 0.3

1.3 ± 0.3

0.9

TG (mmol/l)

1.5 ± 0.7

1.3 ± 0.7

1.2 ± 0.5

0.5

CRP (mg/l)

2.4 ± 1.8

2.8 ± 2.5

1.8 ± 1.0

0.14

SBP (mmHg)

150 ± 21

144 ± 16

145 ± 21

0.9

DBP (mmHg)

83 ± 8

80 ± 8

82 ± 8

0.4

Weight (kg)

87 ± 17

83 ± 15

82 ± 12

0.4

BMI (kg/m2)

30 ± 7

29 ± 6

28 ± 4

0.4

Waist (cm)

103 ± 14

96.8 ± 12

95 ± 9

0.5

fP-glucose (mmol/l)

7.8 ± 1.2

7.1 ± 1.6

7.3 ± 1.3

0.5

fP-insulin (pmol/l)

98 ± 44

74 ± 28

63 ± 21

0.2

AUC glucose (mmol/l·min)

1607 ± 218

1438 ± 350

1437 ± 329

1.0

AUC glucose (mmol/l·min)1

667 ± 186

583 ± 189

558 ± 219

0.6

AUC insulin (nmol/l·min)

30 ± 12

29 ± 12

23 ± 14

0.01

AUC insulin (nmol/l·min)1

18 ± 8

21 ± 11

16 ± 13

0.01

ISI0,120 (mg·l2/mmol·mU·min)

40 ± 9

50 ± 16

56 ± 25

0.2

HOMA2 %B

65 ± 34

65 ± 27

53 ± 18

0.04

HOMA2 %S

59 ± 27

80 ± 42

87 ± 28

0.6

HOMA2 IR

2.0 ± 0.8

1.5 ± 0.6

1.3 ± 0.4

0.2

Diabetic values at OGTT yes/no (n)

12/1

8/5

9/4

1.0


*P for difference between 3 and 6 months in a two-sided t-test with dependent samples, except for Diabetic values at OGTT where P is for difference between diets in Fischer's two-sided exact test with related samples. 1stimulated secretion, area under curve at OGTT with value at 0 minutes as baseline.

Jönsson et al. Cardiovascular Diabetology 2009 8:35   doi:10.1186/1475-2840-8-35

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