Table 2

Parameters of hemostasis, rheology, fibrinolysis, platelet activation and extent and severity of coronary atherosclerosis

all patients

Diabetes mellitus Typ II

control patients

p-value

(n = 150)

(n = 26)

(n = 122)

hemostasis

fibrinogen (mg/dl)

282 ± 64

295 ± 76

278 ± 61

0.1618

prothrombinfragment 1 + 2 (μg/dl)

0,99 ± 0,52

1,01 ± 0,55

0,87 ± 0,37

0.0622

D-Dimere (μg/l)

35 ± 62

31 ± 43

36 ± 65

0.5519

Thrombin-Antithrombin-Komplex (μg/l)

7,6 ± 16

9,6 ± 18,7

7,3 ± 15,5

0.5221

Rheology

plasma viscosity (mPas)

1,30 ± 0,09

1,33 ± 0,09

1,29 ± 0,09

0.0933

erythocyte aggregation M (E)

6,3 ± 1,8

7,3 ± 1,9

6,1 ± 1,8

0.0026

erythocyte aggregation M1 (E)

11,3 ± 2,5

12,8 ± 2,7

11,0 ± 2,3

0.0013

hematocrit (%)

43,5 ± 3,1

42,7 ± 3,7

43,6 ± 2,9

0.1537

fibrinolysis

tissue-plasminogenaktivator (ng/dl)

13,47 ± 3,68

14,18 ± 3,36

13,30 ± 3,77

0.4394

plasminogenactivatorinhibitor (U/ml)

5,78 ± 3,25

7,36 ± 3,24

5,45 ± 3,18

0.0017

plasmin-α2-antiplasmin-complex (μg/dl)

395 ± 152

378 ± 168

396 ± 146

0.4245

platelet activation

platelet count (100.000/ml)

246 ± 71

265 ± 71

242 ± 71

0.1727

von Willebrand-factor (μg/l)

94 ± 31

99 ± 32

93 ± 30

0.3661

plateletfactor 4 (μg/l)

12,7 ± 18,8

9,2 ± 10,9

13,4 ± 20,1

0.9104

β-thromboglobulin (μg/l)

36,68 ± 41,90

30,07 ± 17,57

38,28 ± 45,53

0.7181

GMP 140 (μg/l)

96,36 ± 44,69

94,64 ± 23,41

96,88 ± 48,26

0.2773

Extent and severity of coronary atherosclerosis

total score

1,451 ± 0,591

1,858 ± 0,680

1,379 ± 0,550

0.0182

proximal score

1,399 ± 0,696

1,775 ± 1,037

1,333 ± 0,607

0.2363

distal score

1,457 ± 0,666

1,874 ± 0,647

1,388 ± 0,651

0.0109

1-vessel CAD

31.0%

12.0%

35.0%

2-vessel CAD

37.0%

39.0%

37.0%

3-vessel CAD

32.0%

50.0%

28.0%

0.0306

Jax et al. Cardiovascular Diabetology 2009 8:24   doi:10.1186/1475-2840-8-24