Table 1 |
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|
The changes in DM patients' parameters. |
||||||
| Parameters |
HC |
Metformin (months) |
Rosiglitazone (months) |
|||
|
|
||||||
| 0 |
1 |
2 |
0 |
2 |
||
|
|
||||||
| Fundus |
neg |
neg |
neg |
neg |
neg |
neg |
|
|
||||||
| MAP (mm Hg) |
87.0 ± 2.2 |
99 ± 3.2 |
98.1 ± 1.4 |
99.1 ± 3.6 |
96.1 ± 2.0 |
96.2 ± 0.2 |
| Glucose (mg/dL) |
94.0 ± 11.9 |
228.4 ± 15.1b |
135.3 ± 8.3a,b |
135.9 ± 3.2a,b |
235.2 ± 15.8b |
143.1 ± 14.1a,b |
| HbA1c (μmol/L) |
5.4 ± 0.2 |
8.9 ± 0.3b |
7.2 ± 0.5a,b |
7 ± 0.1a,b |
10.7 ± 0.6b |
7 ± 0.3a,b |
| Calculated GFR |
94.6 ± 2.9 |
99.5 ± 2.1 |
95.7 ± 2.0 |
94.6 ± 2.9 |
95.4 ± 4.8 |
90.1 ± 4.1 |
| Cholesterol (mg/dL) |
205.0 ± 1.7 |
203 ± 8.6 |
188.3 ± 9.9 |
188.3 ± 2.2 |
207.3 ± 9.0 |
195.1 ± 4.8 |
| Triglycerides (mg/dL) |
120.4 ± 3.2 |
153.2 ± 2.1 |
114.6 ± 26.3 |
129.3 ± 6.5 |
190.2 ± 3.5 |
141.4 ± 5.5 |
| HDL (mg/dL) |
58.6 ± 0.7 |
45.9 ± 2.5 |
44.7 ± 3.4 |
43.9 ± 0.9 |
42.04 ± 2.4 |
41.3 ± 0.9 |
| LDL (mg/dL) |
114.6 ± 1.3 |
128.4 ± 7.5 |
120.7 ± 8.7 |
118.6 ± 2.1 |
130.0 ± 7.7 |
114.7 ± 2.6 |
| Hb (g/dL) |
14.3 ± 0.1 |
14.6 ± 0.4 |
14.0 ± 0.6 |
14.8 ± 0.5 |
14.7 ± 0.3 |
14.4 ± 0.1 |
| ALT (U/L) |
20.3 ± 0.5 |
27.3 ± 2.8 |
28.4 ± 5 |
20.3 ± 0.5 |
33.5 ± 6.5 |
24.3 ± 0.7a |
| AST (U/L) |
19.6 ± 0.3 |
19.2 ± 1.5 |
24 ± 3.6 |
19.6 ± 0.3 |
23 ± 3 |
17.4 ± 0.3a |
| ALP (U/L) |
76.2 ± 6.1 |
87.3 ± 4.8b |
73.7 ± 3.9a |
76.2 ± 6.1a |
83.8 ± 4.5b |
75.3 ± 1.5a |
| LDH (U/L) |
283.3 ± 1.9 |
311 ± 17 |
273.2 ± 10.8 |
283.3 ± 1.9 |
270.4 ± 10.8 |
255.8 ± 3.3 |
| Insulin (μU/mL) |
7.6 ± 0.8 |
15.2 ± 1.4b |
13.5 ± 1.0b |
11.1 ± 0.9a,b |
17.5 ± 1.8b |
9.5 ± 0.4a,b |
|
a P < 0.05, treated DM patients vs. untreated DM patients; b P < 0.05, untreated DM patients vs. HC subjects | ||||||
Farah et al. Cardiovascular Diabetology 2008 7:20 doi:10.1186/1475-2840-7-20 |
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