Table 1

Clinical and biochemical data groups in type 2 diabetes treated with 1200 IU α-tocopherol/day or placebo for 4 weeks


α-tocopherol Group (n = 10)
Placebo Group (n = 9)



Day 0
Day 29
Day 0
Day 29

Age (Y)
62.7 (1.81)
__
61.9 (1.92)
__
Diabetes duration
11.1 (2.52)
__
2.6 (0.4)a
__
BMI
29.9 (1.2)
__
29.4 (1.3)
__
WHR
0.92 (0.026)
__
0.94 (0.021)
__
Fasting plasma glucose (mmol/L)
10.7 (0.94)
10.2 (0.86)
7.6 (0.39)a
7.7 (0.41)b
Fasting plasma insulin (mU/L)
49.6 (6.67)
56.2 (9.91)
55.5 (7.81)
54.5 (6.87)
Post-GTT plasma glucose (mmol/L)
20.2 (1.25)c
19.1 (1.26)c
15.1 (0.94)c
15.0 (1.32)c
Post-GTT plasma insulin (mU/L)
135 (37.1)d
124 (31.9)d
218 (47.7)c
261 (87.0)d
HbA1c (%)
8.4 (0.6)
__
7.2 (0.3)
__
Plasma α-tocopherol (μmol/L)
28.9 (1.82)
66.5 (7.26)e
24.4 (1.71)
25.0 (1.78)
8-oxoquanine fluorescence (MFI)
462 (28.0)
456 (19.0)
506 (27.1)
495 (15.2)

Data shown are means (SE)

a p < 0.01 placebo v α-tocopherol; b p < 0.05 placebo v α-tocopherol;

c p < 0.01 Fasting v post-GTT; d p < 0.05 Fasting v post-GTT

e p < 0.01 Day 0 v Day 29

Winterbone et al. Cardiovascular Diabetology 2007 6:8   doi:10.1186/1475-2840-6-8