|
Metabolic Syndrome criteria and Insulin Resistance |
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| Age 3–8 |
Age 9–11 |
Age 12–19 |
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| Higher IR |
Higher IR |
Higher IR |
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| MetS Criterion* |
Yes |
No |
Yes |
No |
Yes |
No |
| n = 41 |
n = 81 |
n = 54 |
n = 110 |
n = 96 |
n = 194 |
|
|
|
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| Waist Circumference % |
95 |
94 (p > .99) |
100. |
93 (p = .05) |
94 |
82 (p = .01) |
| Blood Pressure % |
66 |
64 (p > .99) |
56 |
53 (p = .86) |
65 |
56 (p = .21) |
| Glucose % |
7 |
0 (p = .04) |
11 |
1 (p = .01) |
9 |
1 (p < .01) |
| Triglycerides % |
37 |
33 (p = .88) |
48 |
46 (p = .96) |
41 |
23 (p < .01) |
| HDL % |
44 |
37 (p = .59) |
48 |
45 (p = .79) |
56 |
47 (p = .17) |
|
|
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| Age 3–8 |
Age 9–11 |
Age 12–19 |
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| Number of Components‡ |
Higher IR† |
Higher IR |
Higher IR |
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| n |
% (n) |
n |
% (n) |
n |
% (n) |
|
|
|
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| None |
3 |
0 (0) |
1 |
0 (0) |
12 |
8 (1) |
| Any one |
21 |
29 (6) |
32 |
22 (7) |
67 |
24 (16) |
| Any two |
43 |
35 (15) |
52 |
35 (18) |
88 |
31 (27) |
| Any three |
40 |
35 (14) |
51 |
37 (19) |
80 |
35 (28) |
| Any four |
15 |
40 (6) |
26 |
31 (8) |
38 |
53 (20) |
| All five |
0 |
- |
2 |
100 (2) |
5 |
80 (4) |
|
* Metabolic syndrome (MetS) by modified ATP III criteria: any 3 or more of waist circumference, blood pressure and triglycerides ≥ 90th percentile, HDL ≤ 40 mg/dL, Glucose ≥ 100 mg/dl. Higher insulin resistance (IR): upper tertile of HOMA. Values presented as %. † % of the number (n) within that age group who had insulin resistance (IR), defined as upper tertile of HOMA. ‡Test of association (Spearman's rho) of number of categories with higher IR within age group: age 3–8 (p = .34), age 9–11 (p = .18), age 12–19 (p < .01). | ||||||
Dhuper et al. Cardiovascular Diabetology 2007 6:4 doi:10.1186/1475-2840-6-4 |
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