Table 3

Relationship of covariates to blood glucose and HbA1c measurements


Glucose (mg/dl)
HbA1c (%)



Variables
LS mean ± SE
(95% CI)
P value
LS mean ± SE
(95% CI)
P value

Sex


0.2268


0.8062
     Female
107.80 ± 1.34
(105.15, 110.44)

5.51 ± 0.10
(5.31, 5.71)

     Male
109.70 ± 1.07
(107.58, 111.81)

5.48 ± 0.07
(5.33, 5.64)

Age, years


0.075


0.3041
     20–49
105.09 ± 2.10
(100.96, 109.22)

5.33 ± 0.15
(5.01, 5.64)

     50–59
108.83 ± 1.75
(105.38, 112.27)

5.44 ± 0.13
(5.17, 5.71)

     60–69
109.69 ± 1.43
(106.88, 112.51)

5.62 ± 0.10
(5.42, 5.83)

     70<
111.37 ± 1.32
(108.77, 113.97)

5.61 ± 0.09
(5.42, 5.79)

Medication


0.4579


0.6887
     candesartan cilexetil
110.93 ± 1.31
(108.34, 113.51)

5.62 ± 0.10
(5.41, 5.82)

     losartan potassium
107.73 ± 2.01
(103.77, 111.69)

5.52 ± 0.12
(5.28, 5.77)

     olmesartan medoxomil
106.99 ± 2.24
(102.58, 111.40)

5.37 ± 0.15
(5.06, 5.68)

     telmisartan
108.57 ± 2.16
(104.31, 112.83)

5.43 ± 0.16
(5.10, 5.76)

     valsartan
109.51 ± 1.56
(106.44, 112.59)

5.55 ± 0.12
(5.30, 5.81)

Treatment duration


<.0001


0.6014
     0 = "Baseline"
111.98 ± 1.16
(109.70, 114.27)
reference*
5.51 ± 0.07
(5.37, 5.66)
reference*
     1 = "~3 M"
105.86 ± 1.13
(103.64, 108.09)
<.0001*
5.50 ± 0.07
(5.35, 5.65)
0.8209*
     2 = "3~6 M"
107.78 ± 1.48
(104.87, 110.69)
0.0081*
5.44 ± 0.08
(5.28, 5.61)
0.2582*
     3 = "6~12 M"
109.36 ± 1.63
(106.16, 112.56)
0.1308*
5.54 ± 0.08
(5.37, 5.70)
0.7457*

Abbreviations: HbA1c, hemoglobin A1c; LS means, least squares means; SE, standard error; CI, confidence interval.

*Dunnett-Hsu post-hoc analysis.

Kitamura et al. Cardiovascular Diabetology 2007 6:26   doi:10.1186/1475-2840-6-26