Table 2

Plasma insulin and glucose levels as well as FMD during the oGTT (comparisons by paired Student's test, data represent mean ± standard deviation, #median)


repaglinide
control
p

Fasting Insulin (mU/l)
7.16 ± 4.79
13.06 ± 20.97
n.s.
1 hour Insulin (mU/l)
72.40 ± 62.35
58.32 ± 48.39
n.s.*
2 hour Insulin (mU/l)
120.71 ± 86.78
49.83 ± 36.09
0.013*
Fasting glucose (mg/dl)
106.58 ± 12.38
109.1 ± 16.3
n.s.
1 hour glucose (mg/dl)
222.08 ± 30.05
213.7 ± 29.9
n.s.*
2 hour glucose (mg/dl)
138.33 ± 41.19
172.8 ± 48.4
<0.001***
Fasting FMD (%)
8.18 ± 2.93
7.98 ± 2.24
n.s.
1 hour FMD (%)
5.50 ± 3.11
5.58 ± 2.91
n.s.*
2 hour FMD (%)
7.24 ± 2.57
6.21 ± 2.69
n.s. (0.102)**
1 hour change FMD (%)#
-2.25
-1.95
n.s.*
2 hour change FMD (%)#
-1.05
-1.6
n.s.*
Fasting NMD (%)
15.09 ± 3.76
15.58 ± 3.74
n.s.

*p < 0.001 vs. fasting for both groups

**p = 0.028 vs. fasting for control, n.s. for repaglinide

***p < 0.001 vs. fasting for control, p = 0.005 for repaglinide

Schmoelzer and Wascher Cardiovascular Diabetology 2006 5:9   doi:10.1186/1475-2840-5-9