Table 3

Secondary causes of low HDL-C

1.
Elevated triglycerides.
(Component of metS)

End stage renal disease

Hypothyroidism [also increased total Chol/HDL-C ratio.
2.
Obesity and Overweight. – [waist measurement] –
(Component of metS)

[Visceral obesity in particular]

For every 3 kg. (7 lbs.) weight loss HDL-C increased 1 mg/dL.
3.
Prediabetes and overt Type 2 Diabetes Mellitus.
(Component of metS)
4.
Physical inactivity
(lifestyle choice).
5.
Smoking
(lifestyle choice).
6.
Very high carbohydrate intakes > 50–60% of energy
(lifestyle choice).

[Especially Fructose Containing Soft Drinks.]
7.
Metabolic Syndrome: As potent a risk factor as smoking.
8.
Drugs, such as beta-blockers, anabolic steroids, and progestational agents.

Hayden and Tyagi Cardiovascular Diabetology 2005 4:1   doi:10.1186/1475-2840-4-1