Table 1

General and biochemical parameters of lean and obese Zucker rats (12-14 weeks old)
Lean control Obese control Obese+ROG Lean+HFD Lean+STZ
Body weight (g) 273.83±5.37 439.64±7.34* 425.72±8.26 305.80±3.77* 222.79±3.38*
Plasma glucose (mmol/L) 5.86±0.17 8.88±0.48* 5.94±0.27# 6.22±0.15 >33.00*
Plasma insulin (ng/ml) 0.79±0.02 7.94±1.04* 2.97±0.44# 2.19±0.32* 0.46±0.06*
Mean blood pressure 118.91±1.85 138.26±3.62* 124.85±2.51# 120.59±2.39 129.66±1.51*

Values are means ±SE; n=6. *P < 0.05 vs. lean control rats; #P < 0.05 vs. obese control rats.

Obese rats were treated with rosiglitazone (ROG): 10mg/kg/day for 6 weeks; Lean rats were treated with high fat diet (HFD) and streptozotocin (STZ) for 4 weeks.

Fu et al.

Fu et al. Cardiovascular Diabetology 2014 13:50   doi:10.1186/1475-2840-13-50

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