|
Detailed characteristics of the subjects under study |
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| MEN |
WOMEN |
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|
|
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| Controls N = 10 Mean ± SD |
Hyperlipemic patients N = 20 Mean ± SD |
p |
Controls N = 20 Mean ± SD |
Hyperlipemic patients N = 20 Mean ± SD |
p |
|
|
|
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| BMI |
25.91 ± 3.58 |
28.51 ± 2.60 |
0.030 |
25.36 ± 3.72 |
26.73 ± 3.59 |
0.24 |
| HOMA IR |
1.685 ± 0.771 |
3.137 ± 1.419 |
0.002KS |
1.717 ± 0.893 |
2.694 ± 1.011 |
0.001KS |
| QUICKI |
0,3596 ± 0,0263 |
0,3266 ± 0,0185 |
0,002 |
0,3603 ± 0,0281 |
0,3332 ± 0,0192 |
0,0007 |
| Uric acid (mmol/l) |
270.5 ± 65.4 |
379.9 ± 84.2 |
0.003 |
236.1 ± 67.0 |
270.8 ± 58.9*** |
0.13 |
| Glycemia (mmol/l) |
5.31 ± 0.53 |
6.11 ± 0.95 |
0.029KS |
5.26 ± 0.42 |
5.85 ± 0.70 |
0.0027 |
| Insulin (mIU/l) |
6.96 ± 2.80 |
11.43 ± 4.50 |
0.016KS |
7.33 ± 3.80 |
10.27 ± 3.52 |
0.034KS |
| Proinsulin intact (pmol/l) |
2.68 ± 1.15 |
5.51 ± 2.75 |
0.012KS |
2.51 ± 1.76 |
4.49 ± 3.11 |
0.034KS |
| C-peptide (nmol/l) |
0.66 ± 0.31 |
1.11 ± 0.39 |
0.0148 |
0.75 ± 0.35 |
0.92 ± 0.34 |
0.22KS |
| Leptin (ng/ml) |
3.07 ± 3.38 |
6.21 ± 3.78 |
0.012KS |
16.06 ± 13*** |
17.79 ± 5.9** |
0.17KS |
| TNFα (pg/ml) |
14.2 ± 4.15 |
11.52 ± 2.77 |
0.063KS |
11.65 ± 6.80 |
12.73 ± 9.15 |
0.43KS |
| hFABP (pg/ml) |
3.86 ± 2.47 |
4.53 ± 1.97 |
0.46 |
3.09 ± 1.80 |
3.79 ± 2.00 |
0.41KS |
| ACL-IgG (IU/ml) |
13.08 ± 6.75 |
19.63 ± 16.9 |
0.57KS |
12.28 ± 6.38 |
16.35 ± 16.8 |
0.99KS |
|
BMI = body mass index, HOMA IR and QUICKI = homeostatic indexes of insulin resistance (see Methods), TNFα = tumor necrosis factor α, hFABP = heart fraction of fatty acid binding protein, ACL-IgG = IgG anticardiolipin. Other designations are the same as in Table 1. | ||||||
Lichnovská et al. Cardiovascular Diabetology 2002 1:4 doi:10.1186/1475-2840-1-4 |
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